THERAPEUTIC PLATFORM DEVELOPMENT & DE-RISKING
Drug Delivery & Non-Viral Platforms •  Peptide & Oligonucleotide Therapeutics •  Early Drug Discovery & Preclinical Development 

Early-stage therapeutic platforms often lack established methods, defined performance boundaries, and a clear understanding of how molecular architecture and physicochemical properties influence biological performance.

Advancing these platforms requires fit-for-purpose assays, reproducible workflows, cross-disciplinary scientific judgment, and evidence-based decisions that direct resources toward technically credible designs, applications, and development paths.

I develop and de-risk therapeutic and delivery platforms by translating biological and delivery objectives into testable, reproducible, and reliable technologies. I build the experimental and analytical foundation needed to guide development decisions — whether the goal is to create a technology for a defined purpose or determine what an existing platform can reliably support.

SELECTED PLATFORM WORK

Targeted Delivery Platform Development
Advanced a macrocyclic peptide-enabled targeted LNP platform and evaluated its use across extra-hepatic, ocular and cell-therapy (CAR-M) applications. Established formulation, characterization, stability and reproducibility workflows.  

Peptide nanoparticle development and Productization
Directed development of BAPC™ and LEAP™ self-assembling peptide-nanoparticle platforms, improved synthesis, formulation and QC reproducibility. Conceptualized and supported BAPtofect-25™ productization and advanced nucleic-acid delivery, drug delivery and vaccine-related applications.  

Protein Engineering and Bacterial Systems
Engineered a β-stranded protein ligand that disrupted TolC-mediated multidrug efflux and potentiated antibiotic activity. Supported by protein design, recombinant expression and purification, radio-labeling, protein-folding and membrane-assay workflows. 

Explore selected patents and publications

TECHNICAL FOUNDATION

Molecular Engineering
Peptide chemistry · Protein and ligand engineering · Oligonucleotide Synthesis (ASO/PMO) ·  Bioconjugation

Platform & Delivery
Biomolecular self-assembly · Peptide nanoparticles · Peptide-enabled & targeted lipid nanoparticle (LNP) systems · Drug and nucleic-acid delivery · Assay and workflow development  

Biological systems and Applications
Membrane biophysics · Bacterial membrane proteins and multidrug efflux · Gene-editing and cell-therapy applications · Targeted radiotherapy · Vaccine-related applications